
Jeffrey Wigle
PhD
- Accepting Students: Yes
- Research Category: Newborn, Fetal, and Maternal Health
Contact
- jeffrey.wigle@umanitoba.ca
- 204-471-9006
- Website
- ORCID: 0000-0002-4985-7684
- Research Gate
Current Positions
Professor, Department of Biochemistry and Medical Genetics, University of Manitoba
Principal Investigator, Institute of Cardiovascular Sciences, St. Boniface Hospital Albrechtsen Research Centre
Education
BSc Honours (Biochemistry), Queen's University
PhD (Pharmacology), University of Ottawa
Postdoctoral Fellowship, St. Jude Children's Research Hospital
Research Focus
I study how transcription factors control the growth and differentiation of different cell types during embryonic development. These genetic switches are critical regulators of what a cell becomes. The same pathways that are used in normal embryonic development are frequently disrupted in diseases such as congenital heart disorders.
Research Interests
- Transcription factors
- Cardiovascular development
- Cardiac fibrosis
- Heart valves