Investigator

Ayesha Saleem

PhD, MSc, BSc (Hon)

  • Accepting Students: Yes
  • Research Category: Molecular Physiology

Contact

Current Positions

Associate Professor, Faculty of Kinesiology and Recreation Management (FKRM)
Investigator, The Children’s Hospital Research Institute of Manitoba (CHRIM)
Research Affiliate, Centre on Aging, University of Manitoba
Co-Lead, CHRIM Mentorship Program
Associate Editor, Applied Physiology, Nutrition, and Metabolism (APNM)

Education

Associate Professor, Kinesiology & Recreation Management, University of Manitoba
Postdoctoral Fellowship (Pediatrics), McMaster University
Ph.D. (Molecular, Cellular & Integrative Physiology), York University
M.Sc. (Kinesiology), York University
B.Sc. Honours (Kinesiology & Health Science), York University

Research Focus

The main focus of my research program is to decipher the effects of extracellular vesicles on metabolism and cellular outcomes during conditions of health and disease. These can be physiological (exercise, age), metabolic (cancer, diabetes, obesity), environmental and/or developmental (fetal maternal communication, breast milk, asthma).

Research Interests

- skeletal muscle derived extracellular vesicles (EVs) and mitochondrial biogenesis
- skeletal muscle EVs and lung cancer cell cross-talk
- fetal EVs in fetal-maternal cross-talk
- EVs as markers of mitochondrial disorders
- EVs in pancreatic beta cell senescence and type 2 diabetes
- EVs in breast milk and asthma development