Bioinformatics Core Facility

About

The Bioinformatics Core Facility (BCF) at the Children’s Hospital Research Institute of Manitoba (CHRIM) supports CHRIM researchers in their efforts to improving the health of children and youth.

The facility provides computational expertise and resources for the design and analysis of high throughput omic studies. We employ both standard and novel methods for the analysis of data from transcriptomic, proteomic, metabolomic, and genomic sources as well as support emerging technologies used by CHRIM scientists.

We provide state-of-the-art, secure, regulatory-compliant and customized solutions to address clinical and research needs at CHRIM and stakeholders in the health sciences research cluster. We offer fee-for-service data analyses, bioinformatic support for external funding, customizable training solutions, computational support for independent researchers, and support in the development of novel data processing methods.


Service

We offer three serves models, free consultations, fee-for-service, and grant-funded.

Free Consultations

All bioinformatic projects begin with free consultations. All CHRIM researchers or others conduction research aligned with CHRIM’s mission receive free consultations regarding their bioinformatic needs. If you are unsure, please reach out to us for a no-obligation initial consultation.

Also, please consult with us before acquiring your data! Remember this gem from Ronald Fisher’s 1938 address to the first Indian Statistical Congress: “To consult the statistician after an experiment is finished is often merely to ask him to conduct a post-mortem examination. He can perhaps say what the experiment died of”.

Where possible, seek bioinformatics services at the beginning of the project so that we can have detailed discussions regarding the design of experiments in view of the biological question and their context.

Fee-for-Service

The fee-for-service module involves discussions with PIs regarding their data analysis needs after an initial meeting, an intake form will be completed (please refer to the intake form here). This model is suitable for either small research projects or for repetition of very standard workflows.

Grant-Funded Support

Large externally funded projects can be supported through subcontracts to the facility. We can assist in all phases of such projects including, proposal development, grant submission, and the research itself.


Training

We offer continuing training for students and researchers to analyze their data using various bioinformatics tools. We also accept students to train within the facility to develop novel tools for the analysis of omics data.

We also offer all CHRIM researchers individual training on accessing and utilizing CHRIM high-performance computing (HPC) resources.

offer continuing training for students and researchers to analyze their data using various bioinformatics tools. We also accept students to train within the facility to develop novel tools for the analysis of – omics data.

Our research aims to fill technological gaps in the -omics field that limit access to existing correlations and interplay between multiple levels of a biological system’s descriptors.
 


Research and Method Development

Our research aim is to fill gaps in the -omics field that limit CHRIM researchers in their research efforts. We have several options in assisting researchers. We can provide custom training to graduate students. Please contact us for additional information.